Dr. Tianjiao Chu oversees Signatures collection of data and its use to create analytics and business intelligence models. Chu received his PhD, in Logic, Computation, and Methodology, from Carnegie Mellon University and went on to do his Postdoctoral Fellow and Research Scientist in data mining.

Chu applies his 12 years’ experience as a statistician to excel in his role as Chief Analytical Officer for Signature. A major goal of Dr. Chu’s research is to develop a sophisticated statistical model for next-generation sequencing and to examine the limitations of this technology, exploring its applications as a diagnostic tool. He also uses informatics tools to analyze mRNA and protein datasets.

Chu has worked closely with Dr. David Peters, Co-Founder and CSO for Signature, for years and created tools in the form of a proprietary analytics model that allowed Peters to search for the maternally-inherited fetal DNA in a sample mixture. Through their collaboration and dedication, the team was able to identify Down Syndrome and even applied the technology to identify other fetal aneuploidies—also described as chromosomal abnormalities.

“Working as a biostatistician in clinical research has allowed me to take complex, mathematical findings of clinical trials and research-related data and translate them into valuable information that is used to make public health decisions.” - Dr. Tianjiao Chu, PhD